There are multiple stages of Multiple System Atrophy (MSA) a person has to go through, each presenting different challenges for individuals affected by the condition.

While the stages can vary between individuals, a general overview includes three main phases:

Early Stage:

• In the early stage of MSA, symptoms may be mild and may not significantly interfere with daily activities.
• Common signs include problems with balance and coordination, slight difficulty with movement, and possibly changes in blood pressure regulation.
• Individuals may still be able to perform routine tasks independently during this stage.

Intermediate Stage:

• As MSA increases, symptoms become more noticeable and can impact daily life to a greater extent.
• Issues with balance and coordination worsen, leading to increased difficulties with walking and performing motor tasks.
• Autonomic dysfunction becomes more noticeable, resulting in problems with blood pressure control, bladder and bowel function, and temperature regulation.
• Individuals may require assistance with some activities of daily living, and mobility aids like canes or walkers may become necessary.

Advanced Stage:

• The advanced stage of MSA is described by severe and overall impairment in both motor and autonomic functions.
• Mobility becomes highly restricted, often necessitating the use of wheelchairs for movement.
• Communication may be challenging due to speech and swallowing difficulties.
• Autonomic dysfunction becomes more pronounced, leading to increased vulnerability to infections and respiratory issues.
• Daily activities become highly dependent on the assistance of caretakers

Throughout these stages, it’s important to understand that the condition of MSA can vary between individuals. Some may experience a more rapid decline, while others may progress more slowly.

Additionally, supportive care and symptom management play a vital role in improving the quality of life of a person with MSA, regardless of the stage.

Regular communication with doctors and the involvement of caretakers is important in providing complete care and support for those living with MSA.

Dr. Navin Tiwari
Consulting Neurologist